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Four best friends, with four different personalities, have issues of their own. Deidre is fascinated by her sexuality and has many boyfriend problems. Madge is unhappily overweight and has overprotective parents. Annie boozes and does drugs, and runs away from her abusive father, a policeman. Jeanie has to take care of them and is fighting with her divorced mother. The only way to loosen up, and forget all the bad things happening in their lives, is to party and have fun. Jeanie is ready to grow up and wants to stop acting like a child. Annie is the worst of them all and Jeanie is worried about her the most. She risks her neck more than once trying to keep Annie clean and free from trouble. However, Annie's unstable behavior and flare ups keeps everyone on edge.